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HFC-125 (Pentafluoroethane)


Synonyms: 1,1,1,2,2-Pentafluoroethane (IUPAC); Hydrofluorocarbon 125;  R-125; FC-125; ECARO-25; FE-25; NAF S 125
De: Pentafluorethan   ES: Pentafluoroetano   Fr: Pentafluoroéthane
CAS No.: 354-33-6   EC No: 206-557-8   RTECS No.: KI6365000
Molecular Weight:  120.022
Molecular Formula: C2HF5
Structural Formula:hfc-125 (pentafluoroethane)
b.p. (1 atm): -48.45°C
m.p.: -103°C
ODP: 0
GWP: 3400 (CO2=1)
Chemical and Physical properties: Stable in normal condition, HFC-125 is odorless, colorless, electrically non-conductive, non-corrosive, and leaves no residue


HFC-125 (pentafluoroethane) is made by process of gas-phase fluoridation between perchloroethylene (PCE) and hydrofluoric acid (HF). The intermediates of reaction are HCFC-123 and HCFC-124


1) With zero ODP, HFC-125 is mainly used as a component of azeotropic blend refrigerant such as R-404a, R-407a, R-407b, R-407c, R-407d, R-410a and R410b (for more information, please see …).
2) HFC-125 is also used in clean agent fire suppression system in enclosed space with situations where water from a fire sprinkler would damage expensive equipment or where water-based fire protection is impractical, such as museums, banks, clean rooms and hospitals. It is altenative for CFC-502, Halon-1211 and Halon-1301


Parameters Specification
HFC-125 purity 99.8% min
moisture 10 ppm max
Acidity as (HF) 1 ppm max.
Evaporation residues 0.01%max
Visible foreign substance no

Standard Packaging

780kg/steel cylinder; ISO Tank

Packaging of HFC-125 gas

Risks and Safety Information

UN 3220. Class 2.2 PG unknown
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Do not heat above 52°C (125°F).
For other information, please see MSDS


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